John M Stewart Selected Research

BKM-570

12/2010	Strong cytotoxic effect of the bradykinin antagonist BKM-570 in ovarian cancer cells--analysis of the molecular mechanisms of its antiproliferative action.
8/2005	Combination cancer chemotherapy with one compound: pluripotent bradykinin antagonists.

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John M Stewart Research Topics

Disease

11	Neoplasms (Cancer) 01/2022 - 04/2002
5	Lung Neoplasms (Lung Cancer) 01/2024 - 05/2002
5	Prostatic Neoplasms (Prostate Cancer) 01/2018 - 04/2002
4	Tics (Tic) 02/2008 - 02/2002
3	Inflammation (Inflammations) 03/2004 - 04/2002
2	Lymphoma (Lymphomas) 01/2020 - 01/2013
2	Ovarian Neoplasms (Ovarian Cancer) 01/2018 - 12/2010
2	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2013 - 04/2012
2	Carcinoma (Carcinomatosis) 01/2013 - 12/2010
2	Pulmonary Hypertension 08/2005 - 04/2002
1	Choriocarcinoma 01/2024
1	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 01/2020
1	Breast Neoplasms (Breast Cancer) 01/2018
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 05/2014
1	Leukemia 01/2013
1	Endometrioid Carcinoma 12/2010
1	Ovarian Epithelial Carcinoma 12/2010
1	Pericardial Effusion 08/2005
1	Vascular Diseases (Vascular Disease) 08/2005
1	Right Ventricular Hypertrophy 08/2005
1	Psychogenic Polydipsia 05/2004
1	Polyuria 05/2004
1	Polydipsia 05/2004
1	Pain (Aches) 03/2004
1	Necrosis 09/2003
1	Sarcoma (Soft Tissue Sarcoma) 04/2003
1	Hypoxia (Hypoxemia) 04/2002
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 04/2002
1	Hypertrophy 04/2002

Drug/Important Bio-Agent (IBA)

8	BradykininIBA 12/2010 - 04/2002
7	Peptides (Polypeptides)IBA 01/2013 - 12/2002
7	Bradykinin Receptor AntagonistsIBA 12/2010 - 04/2002
3	AcidsIBA 01/2009 - 02/2002
3	lysyllysine (Lys-Lys)IBA 02/2008 - 09/2005
2	Proteins (Proteins, Gene)FDA Link 01/2018 - 05/2004
2	BKM-570IBA 12/2010 - 08/2005
2	AmidesIBA 12/2010 - 01/2009
2	Hydroxyproline (4 Hydroxyproline)IBA 02/2008 - 02/2002
2	amastatinIBA 04/2006 - 09/2005
2	Metalloproteases (Metalloproteinases)IBA 08/2005 - 12/2002
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 12/2002 - 04/2002
2	NeuropeptidesIBA 05/2002 - 04/2002
1	Etoposide (VP 16)FDA LinkGeneric 01/2024
1	Carboplatin (JM8)FDA LinkGeneric 01/2024
1	Alkaline PhosphataseIBA 01/2022
1	AntigensIBA 01/2022
1	BilirubinIBA 01/2022
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2022
1	CalciumIBA 01/2020
1	Capsules (Microcapsules)IBA 01/2020
1	Phenobarbital (Luminal)FDA Link 01/2020
1	Calcium Channels (Calcium Channel)IBA 01/2018
1	Messenger RNA (mRNA)IBA 01/2018
1	Indicators and Reagents (Reagents)IBA 01/2013
1	SOR-C13IBA 01/2013
1	VaccinesIBA 04/2012
1	ChitosanIBA 04/2012
1	AlginatesIBA 04/2012
1	PlatinumIBA 12/2010
1	Cisplatin (Platino)FDA LinkGeneric 12/2010
1	taxaneIBA 12/2010
1	B10324IBA 02/2008
1	Carboxylic AcidsIBA 02/2008
1	1,2,3,4-tetrahydroisoquinolineIBA 02/2008
1	CD13 Antigens (Alanine Aminopeptidase)IBA 04/2006
1	Chromogenic CompoundsIBA 04/2006
1	Arginine (L-Arginine)FDA Link 04/2006
1	B-9958IBA 04/2006
1	B9972IBA 08/2005
1	Bradykinin Receptors (Bradykinin Receptor)IBA 08/2005
1	Matrix Metalloproteinases (MMPs)IBA 08/2005
1	Bradykinin B2 ReceptorIBA 08/2005
1	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 05/2004
1	Captopril (Capoten)FDA LinkGeneric 05/2004
1	SilverIBA 09/2003
1	Coloring Agents (Dyes)IBA 09/2003
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2002
1	Hormones (Hormone)IBA 12/2002
1	CU201IBA 05/2002
1	Antineoplastic Agents (Antineoplastics)IBA 05/2002
1	Semaxinib (SU5416)IBA 04/2002
1	CaspasesIBA 04/2002
1	benzyloxycarbonyl-asparagine (Z-Asp)IBA 04/2002
1	Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA 04/2002
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 02/2002
1	Amino Acids FDA Link 02/2002

Therapy/Procedure

3	Drug Therapy (Chemotherapy) 12/2010 - 04/2003
2	Therapeutics 01/2020 - 05/2002
1	Radiotherapy 01/2024
1	Breast Implants (Breast Implant) 01/2020
1	Heterologous Transplantation (Xenotransplantation) 05/2014
1	Combination Drug Therapy (Combination Chemotherapy) 08/2005